Rifamycin O

Rifamycin O class: Core intermediate for anti-tuberculosis drug synthesis and a key tool in antibiotic research

Product Information


  • 产品名 Rifamycin O
  • 化学式 C₃₉H₄₇NO₁₄
  • CAS 14487-05-9
  • 执行标准 Q/XJYLH 22-2026
  • 产品特性 Beige to dark orange powder
  • 产品包装 25kg/drum

Product Overview and Characteristics

This product has dual uses in the pharmaceutical field. As a chemical raw material, it is a key intermediate produced from rifamycin B via oxidation reaction and can be used for the further synthesis of other rifamycin derivatives. At the same time, rifamycin O itself also possesses certain antibacterial activity and can serve as a selective inhibitor of bacterial DNA-dependent RNA polymerase, being effective against Mycobacterium species (including Mycobacterium tuberculosis). Studies have shown that it has good in vitro activity and in vivo efficacy against difficult-to-treat Mycobacterium abscessus infections. In the laboratory, this product can also be used as a tool compound for studying the mechanism of action of antibiotics and the structure-activity relationships of rifamycin compounds.

Pharmaceutical synthesis intermediate

It is a key intermediate produced from rifamycin B via oxidation reaction and can be used for the further synthesis of other rifamycin derivatives, holding important application value in the pharmaceutical industry.

Antibacterial activity

It itself possesses certain antibacterial activity and can serve as a selective inhibitor of bacterial DNA-dependent RNA polymerase, being effective against Mycobacterium species (including Mycobacterium tuberculosis), and has good in vitro activity and in vivo efficacy against difficult-to-treat Mycobacterium abscessus infections.

Scientific research tool

In the laboratory, it is used as a tool compound for studying the mechanism of action of antibiotics and the structure-activity relationships of rifamycin compounds, contributing to the research and development of novel antibacterial drugs.